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Fluorescence Quenching of Alpha-Fetoprotein by Gold Nanoparticles: Effect of Dielectric Shell on Non-Radiative Decay

Fluorescence quenching spectrometry was applied to study the interactions between gold colloidal nanoparticles and alpha-fetoprotein (AFP). Experimental results show that the gold nanoparticles can quench the fluorescence emission of adsorbed AFP effectively. Furthermore, the intensity of fluorescen...

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Detalles Bibliográficos
Autores principales: Zhu, Jian, Li, Jian-jun, Wang, A-qing, Chen, Yu, Zhao, Jun-wu
Formato: Texto
Lenguaje:English
Publicado: Springer 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920401/
https://www.ncbi.nlm.nih.gov/pubmed/20730117
http://dx.doi.org/10.1007/s11671-010-9668-0
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author Zhu, Jian
Li, Jian-jun
Wang, A-qing
Chen, Yu
Zhao, Jun-wu
author_facet Zhu, Jian
Li, Jian-jun
Wang, A-qing
Chen, Yu
Zhao, Jun-wu
author_sort Zhu, Jian
collection PubMed
description Fluorescence quenching spectrometry was applied to study the interactions between gold colloidal nanoparticles and alpha-fetoprotein (AFP). Experimental results show that the gold nanoparticles can quench the fluorescence emission of adsorbed AFP effectively. Furthermore, the intensity of fluorescence emission peak decreases monotonously with the increasing gold nanoparticles content. A mechanism based on surface plasmon resonance–induced non-radiative decay was investigated to illuminate the effect of a dielectric shell on the fluorescence quenching ability of gold nanoparticles. The calculation results show that the increasing dielectric shell thickness may improve the monochromaticity of fluorescence quenching. However, high energy transfer efficiency can be obtained within a wide wavelength band by coating a thinner dielectric shell.
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spelling pubmed-29204012010-08-20 Fluorescence Quenching of Alpha-Fetoprotein by Gold Nanoparticles: Effect of Dielectric Shell on Non-Radiative Decay Zhu, Jian Li, Jian-jun Wang, A-qing Chen, Yu Zhao, Jun-wu Nanoscale Res Lett Nano Express Fluorescence quenching spectrometry was applied to study the interactions between gold colloidal nanoparticles and alpha-fetoprotein (AFP). Experimental results show that the gold nanoparticles can quench the fluorescence emission of adsorbed AFP effectively. Furthermore, the intensity of fluorescence emission peak decreases monotonously with the increasing gold nanoparticles content. A mechanism based on surface plasmon resonance–induced non-radiative decay was investigated to illuminate the effect of a dielectric shell on the fluorescence quenching ability of gold nanoparticles. The calculation results show that the increasing dielectric shell thickness may improve the monochromaticity of fluorescence quenching. However, high energy transfer efficiency can be obtained within a wide wavelength band by coating a thinner dielectric shell. Springer 2010-06-15 /pmc/articles/PMC2920401/ /pubmed/20730117 http://dx.doi.org/10.1007/s11671-010-9668-0 Text en Copyright © 2010 The Author(s) https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Nano Express
Zhu, Jian
Li, Jian-jun
Wang, A-qing
Chen, Yu
Zhao, Jun-wu
Fluorescence Quenching of Alpha-Fetoprotein by Gold Nanoparticles: Effect of Dielectric Shell on Non-Radiative Decay
title Fluorescence Quenching of Alpha-Fetoprotein by Gold Nanoparticles: Effect of Dielectric Shell on Non-Radiative Decay
title_full Fluorescence Quenching of Alpha-Fetoprotein by Gold Nanoparticles: Effect of Dielectric Shell on Non-Radiative Decay
title_fullStr Fluorescence Quenching of Alpha-Fetoprotein by Gold Nanoparticles: Effect of Dielectric Shell on Non-Radiative Decay
title_full_unstemmed Fluorescence Quenching of Alpha-Fetoprotein by Gold Nanoparticles: Effect of Dielectric Shell on Non-Radiative Decay
title_short Fluorescence Quenching of Alpha-Fetoprotein by Gold Nanoparticles: Effect of Dielectric Shell on Non-Radiative Decay
title_sort fluorescence quenching of alpha-fetoprotein by gold nanoparticles: effect of dielectric shell on non-radiative decay
topic Nano Express
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920401/
https://www.ncbi.nlm.nih.gov/pubmed/20730117
http://dx.doi.org/10.1007/s11671-010-9668-0
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