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In situ visualization and dynamics of newly synthesized proteins in rat hippocampal neurons
Protein translation has been implicated in different forms of synaptic plasticity but direct in situ visualization of new proteins is limited to one or two proteins at a time. Here we describe a metabolic labeling approach based upon incorporation of non-canonical amino acids into proteins followed...
Autores principales: | Dieterich, Daniela C., Hodas, Jennifer J.L., Gouzer, Geraldine, Shadrin, Ilya Y., Ngo, John T., Triller, Antoine, Tirrell, David A., Schuman, Erin M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920597/ https://www.ncbi.nlm.nih.gov/pubmed/20543841 http://dx.doi.org/10.1038/nn.2580 |
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