‘A mover and a shaker’: 53BP1 allows DNA doublestrand breaks a chance to dance and unite

The DNA damage response mediator protein, p53-binding protein 1 (53BP1), is dispensable for the repair of most DNA doublestrand breaks (DSBs) induced by ionising radiation. However, two recent studies have shown that 53BP1 is required for rejoining of distant DSB ends and that it promotes the moveme...

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Detalles Bibliográficos
Autores principales: Goodarzi, Aaron A, Jeggo, Penny A
Formato: Texto
Lenguaje:English
Publicado: Biology Reports Ltd 2009
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920668/
https://www.ncbi.nlm.nih.gov/pubmed/20948664
http://dx.doi.org/10.3410/B1-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920668/
https://www.ncbi.nlm.nih.gov/pubmed/20948664
http://dx.doi.org/10.3410/B1-21

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