The inflammasome and alum-mediated adjuvanticity

Recent reports have implicated the NLRP3-associated inflammasome in the adjuvanticity of alum. Here, we summarize the major findings and ask what this may mean for improving human vaccination.

Detalles Bibliográficos
Autores principales: Kang, Suk-Jo, Locksley, Richard M
Formato: Texto
Lenguaje:English
Publicado: Biology Reports Ltd 2009
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920669/
https://www.ncbi.nlm.nih.gov/pubmed/20948671
http://dx.doi.org/10.3410/B1-15
Descripción
Sumario:Recent reports have implicated the NLRP3-associated inflammasome in the adjuvanticity of alum. Here, we summarize the major findings and ask what this may mean for improving human vaccination.

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