G-protein-coupled receptor structure: what can we learn?

The first, long-awaited, structures of non-visual G-protein-coupled receptors have provided important insights into the process of ligand binding and receptor activation. Here I explore the technological advances that enabled the resolution of the crystal structures of the β(1)- and β(2)-adrenergic...

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Detalles Bibliográficos
Autor principal: Tobin, Andrew B
Formato: Texto
Lenguaje:English
Publicado: Biology Reports Ltd 2009
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920676/
https://www.ncbi.nlm.nih.gov/pubmed/20948675
http://dx.doi.org/10.3410/B1-11
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author Tobin, Andrew B
author_facet Tobin, Andrew B
author_sort Tobin, Andrew B
collection PubMed
description The first, long-awaited, structures of non-visual G-protein-coupled receptors have provided important insights into the process of ligand binding and receptor activation. Here I explore the technological advances that enabled the resolution of the crystal structures of the β(1)- and β(2)-adrenergic receptors, and review what we have learnt and what is still to be discovered.
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spelling pubmed-29206762010-10-14 G-protein-coupled receptor structure: what can we learn? Tobin, Andrew B F1000 Biol Rep Review Article The first, long-awaited, structures of non-visual G-protein-coupled receptors have provided important insights into the process of ligand binding and receptor activation. Here I explore the technological advances that enabled the resolution of the crystal structures of the β(1)- and β(2)-adrenergic receptors, and review what we have learnt and what is still to be discovered. Biology Reports Ltd 2009-02-24 /pmc/articles/PMC2920676/ /pubmed/20948675 http://dx.doi.org/10.3410/B1-11 Text en © 2009 Biology Reports Ltd http://creativecommons.org/licenses/by-nc/3.0/legalcode This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. You may not use this work for commercial purposes
spellingShingle Review Article
Tobin, Andrew B
G-protein-coupled receptor structure: what can we learn?
title G-protein-coupled receptor structure: what can we learn?
title_full G-protein-coupled receptor structure: what can we learn?
title_fullStr G-protein-coupled receptor structure: what can we learn?
title_full_unstemmed G-protein-coupled receptor structure: what can we learn?
title_short G-protein-coupled receptor structure: what can we learn?
title_sort g-protein-coupled receptor structure: what can we learn?
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920676/
https://www.ncbi.nlm.nih.gov/pubmed/20948675
http://dx.doi.org/10.3410/B1-11
work_keys_str_mv AT tobinandrewb gproteincoupledreceptorstructurewhatcanwelearn

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