The ABCB1 transporter gene and antidepressant response

P-glycoprotein, encoded by the ABCB1 gene, may modulate the brain concentration of several antidepressants. Functional genetic variation is thought to exist in this gene, and here we review several studies that have attempted to associate this variation with clinical response to antidepressant treat...

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Detalles Bibliográficos
Autores principales: Peters, Eric J, Reus, Victor, Hamilton, Steven P
Formato: Texto
Lenguaje:English
Publicado: Biology Reports Ltd 2009
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920683/
https://www.ncbi.nlm.nih.gov/pubmed/20948663
http://dx.doi.org/10.3410/B1-23
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author Peters, Eric J
Reus, Victor
Hamilton, Steven P
author_facet Peters, Eric J
Reus, Victor
Hamilton, Steven P
author_sort Peters, Eric J
collection PubMed
description P-glycoprotein, encoded by the ABCB1 gene, may modulate the brain concentration of several antidepressants. Functional genetic variation is thought to exist in this gene, and here we review several studies that have attempted to associate this variation with clinical response to antidepressant treatment.
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spelling pubmed-29206832010-10-14 The ABCB1 transporter gene and antidepressant response Peters, Eric J Reus, Victor Hamilton, Steven P F1000 Biol Rep Review Article P-glycoprotein, encoded by the ABCB1 gene, may modulate the brain concentration of several antidepressants. Functional genetic variation is thought to exist in this gene, and here we review several studies that have attempted to associate this variation with clinical response to antidepressant treatment. Biology Reports Ltd 2009-03-24 /pmc/articles/PMC2920683/ /pubmed/20948663 http://dx.doi.org/10.3410/B1-23 Text en © 2009 Biology Reports Ltd http://creativecommons.org/licenses/by-nc/3.0/legalcode This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. You may not use this work for commercial purposes
spellingShingle Review Article
Peters, Eric J
Reus, Victor
Hamilton, Steven P
The ABCB1 transporter gene and antidepressant response
title The ABCB1 transporter gene and antidepressant response
title_full The ABCB1 transporter gene and antidepressant response
title_fullStr The ABCB1 transporter gene and antidepressant response
title_full_unstemmed The ABCB1 transporter gene and antidepressant response
title_short The ABCB1 transporter gene and antidepressant response
title_sort abcb1 transporter gene and antidepressant response
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920683/
https://www.ncbi.nlm.nih.gov/pubmed/20948663
http://dx.doi.org/10.3410/B1-23
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