Tip-DC Development during Parasitic Infection Is Regulated by IL-10 and Requires CCL2/CCR2, IFN-γ and MyD88 Signaling

The development of classically activated monocytic cells (M1) is a prerequisite for effective elimination of parasites, including African trypanosomes. However, persistent activation of M1 that produce pathogenic molecules such as TNF and NO contributes to the development of trypanosome infection-as...

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Detalles Bibliográficos
Autores principales: Bosschaerts, Tom, Guilliams, Martin, Stijlemans, Benoît, Morias, Yannick, Engel, Daniel, Tacke, Frank, Hérin, Michel, De Baetselier, Patrick, Beschin, Alain
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920868/
https://www.ncbi.nlm.nih.gov/pubmed/20714353
http://dx.doi.org/10.1371/journal.ppat.1001045

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