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Characterisation of prostate cancer lesions in heterozygous Men1 mutant mice
BACKGROUND: Mutations of the MEN1 gene predispose to multiple endocrine neoplasia type 1 (MEN1) syndrome. Our group and others have shown that Men1 disruption in mice recapitulates MEN1 pathology. Intriguingly, rare lesions in hormone-dependent tissues, such as prostate and mammary glands, were also...
Autores principales: | Seigne, Christelle, Fontanière, Sandra, Carreira, Christine, Lu, Jieli, Tong, Wei-Ming, Fontanière, Bernard, Wang, Zhao-Qi, Zhang, Chang Xian, Frappart, Lucien |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920881/ https://www.ncbi.nlm.nih.gov/pubmed/20663219 http://dx.doi.org/10.1186/1471-2407-10-395 |
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