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Characterisation of prostate cancer lesions in heterozygous Men1 mutant mice

BACKGROUND: Mutations of the MEN1 gene predispose to multiple endocrine neoplasia type 1 (MEN1) syndrome. Our group and others have shown that Men1 disruption in mice recapitulates MEN1 pathology. Intriguingly, rare lesions in hormone-dependent tissues, such as prostate and mammary glands, were also...

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Detalles Bibliográficos
Autores principales: Seigne, Christelle, Fontanière, Sandra, Carreira, Christine, Lu, Jieli, Tong, Wei-Ming, Fontanière, Bernard, Wang, Zhao-Qi, Zhang, Chang Xian, Frappart, Lucien
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920881/
https://www.ncbi.nlm.nih.gov/pubmed/20663219
http://dx.doi.org/10.1186/1471-2407-10-395

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