mot-2–Mediated Cross Talk between Nuclear Factor-κB and p53 Is Involved in Arsenite-Induced Tumorigenesis of Human Embryo Lung Fibroblast Cells

BACKGROUND: Inactivation of p53 is involved in arsenite-induced tumorigenesis; however, the molecular mechanisms remain poorly understood. OBJECTIVE: We investigated the molecular mechanisms underlying the inactivation of p53 and neoplastic transformation induced by arsenite in human embryo lung fib...

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Detalles Bibliográficos
Autores principales: Li, Yuan, Xu, Yuan, Ling, Min, Yang, Ye, Wang, Shoulin, Li, Zhong, Zhou, Jianwei, Wang, Xinru, Liu, Qizhan
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920912/
https://www.ncbi.nlm.nih.gov/pubmed/20199942
http://dx.doi.org/10.1289/ehp.0901677

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