Selective control of amino acid metabolism by the GCN2 eIF2 kinase pathway in Saccharomyces cerevisiae

BACKGROUND: When eukaryotic cells are deprived of amino acids, uncharged tRNAs accumulate and activate the conserved GCN2 protein kinase. Activated Gcn2p up-regulates the general amino acid control pathway through phosphorylation of the translational initiation factor eIF2. In Saccharomyces cerevisi...

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Detalles Bibliográficos
Autores principales: Zaborske, John M, Wu, Xiaochen, Wek, Ronald C, Pan, Tao
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921344/
https://www.ncbi.nlm.nih.gov/pubmed/20684782
http://dx.doi.org/10.1186/1471-2091-11-29

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921344/
https://www.ncbi.nlm.nih.gov/pubmed/20684782
http://dx.doi.org/10.1186/1471-2091-11-29

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