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Selective control of amino acid metabolism by the GCN2 eIF2 kinase pathway in Saccharomyces cerevisiae

BACKGROUND: When eukaryotic cells are deprived of amino acids, uncharged tRNAs accumulate and activate the conserved GCN2 protein kinase. Activated Gcn2p up-regulates the general amino acid control pathway through phosphorylation of the translational initiation factor eIF2. In Saccharomyces cerevisi...

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Detalles Bibliográficos
Autores principales:	Zaborske, John M, Wu, Xiaochen, Wek, Ronald C, Pan, Tao
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921344/ https://www.ncbi.nlm.nih.gov/pubmed/20684782 http://dx.doi.org/10.1186/1471-2091-11-29

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