Optimization of total protein and activity assays for the detection of MMP-12 in induced human sputum

BACKGROUND: Proteolysis of matrix components, in particular elastin, is a major contributing factor to the development of lung diseases such as emphysema and chronic obstructive pulmonary disease (COPD). MMP-12 (macrophage elastase) is a protease known to be involved in the progression of lung disea...

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Detalles Bibliográficos
Autores principales: LaPan, Peter, Brady, Jeff, Grierson, Christal, Fleming, Margaret, Miller, Doug, Sypek, Joe, Fu, Bin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Technical Advance
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921351/
https://www.ncbi.nlm.nih.gov/pubmed/20678199
http://dx.doi.org/10.1186/1471-2466-10-40

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921351/
https://www.ncbi.nlm.nih.gov/pubmed/20678199
http://dx.doi.org/10.1186/1471-2466-10-40

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