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HCV(+) Hepatocytes Induce Human Regulatory CD4(+) T Cells through the Production of TGF-β

BACKGROUND: Hepatitis C Virus (HCV) is remarkably efficient at establishing persistent infection and is associated with the development of chronic liver disease. Impaired T cell responses facilitate and maintain persistent HCV infection. Importantly, CD4(+) regulatory T cells (Tregs) act by dampenin...

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Detalles Bibliográficos
Autores principales: Hall, Caroline H. T., Kassel, Rachel, Tacke, Robert S., Hahn, Young S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921368/
https://www.ncbi.nlm.nih.gov/pubmed/20730048
http://dx.doi.org/10.1371/journal.pone.0012154