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HCV(+) Hepatocytes Induce Human Regulatory CD4(+) T Cells through the Production of TGF-β
BACKGROUND: Hepatitis C Virus (HCV) is remarkably efficient at establishing persistent infection and is associated with the development of chronic liver disease. Impaired T cell responses facilitate and maintain persistent HCV infection. Importantly, CD4(+) regulatory T cells (Tregs) act by dampenin...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921368/ https://www.ncbi.nlm.nih.gov/pubmed/20730048 http://dx.doi.org/10.1371/journal.pone.0012154 |