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Estimating the individualized HIV-1 genetic barrier to resistance using a nelfinavir fitness landscape

BACKGROUND: Failure on Highly Active Anti-Retroviral Treatment is often accompanied with development of antiviral resistance to one or more drugs included in the treatment. In general, the virus is more likely to develop resistance to drugs with a lower genetic barrier. Previously, we developed a me...

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Detalles Bibliográficos
Autores principales:	Theys, Kristof, Deforche, Koen, Beheydt, Gertjan, Moreau, Yves, van Laethem, Kristel, Lemey, Philippe, Camacho, Ricardo J, Rhee, Soo-Yon, Shafer, Robert W, Van Wijngaerden, Eric, Vandamme, Anne-Mieke
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921410/ https://www.ncbi.nlm.nih.gov/pubmed/20682040 http://dx.doi.org/10.1186/1471-2105-11-409

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