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Modeling of B cell Synapse Formation by Monte Carlo Simulation Shows That Directed Transport of Receptor Molecules Is a Potential Formation Mechanism
The formation of the protein segregation structure known as the “immunological synapse” in the contact region between B cells and antigen presenting cells appears to precede antigen (Ag) uptake by B cells. The mature B cell synapse consists of a central cluster of B cell receptor/Antigen (BCR/Ag) co...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
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Springer US
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921492/ https://www.ncbi.nlm.nih.gov/pubmed/20730058 http://dx.doi.org/10.1007/s12195-010-0123-1 |