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Lung function and blood markers of nutritional status in non-COPD aging men with smoking history: A cross-sectional study

PURPOSE: Cigarette smoking and advanced age are well known as risk factors for chronic obstructive pulmonary disease (COPD), and nutritional abnormalities are important in patients with COPD. However, little is known about the nutritional status in non-COPD aging men with smoking history. We therefo...

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Autores principales: Shiozawa, Nobuyoshi, Hayashimoto, Kanae, Suzuki, Etsuji, Kikuchi, Hiroshi, Takata, Shingo, Ashida, Kozo, Watanabe, Masutaka, Hosaki, Yasuhiro, Mitsunobu, Fumihiro
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921691/
https://www.ncbi.nlm.nih.gov/pubmed/20714377
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author Shiozawa, Nobuyoshi
Hayashimoto, Kanae
Suzuki, Etsuji
Kikuchi, Hiroshi
Takata, Shingo
Ashida, Kozo
Watanabe, Masutaka
Hosaki, Yasuhiro
Mitsunobu, Fumihiro
author_facet Shiozawa, Nobuyoshi
Hayashimoto, Kanae
Suzuki, Etsuji
Kikuchi, Hiroshi
Takata, Shingo
Ashida, Kozo
Watanabe, Masutaka
Hosaki, Yasuhiro
Mitsunobu, Fumihiro
author_sort Shiozawa, Nobuyoshi
collection PubMed
description PURPOSE: Cigarette smoking and advanced age are well known as risk factors for chronic obstructive pulmonary disease (COPD), and nutritional abnormalities are important in patients with COPD. However, little is known about the nutritional status in non-COPD aging men with smoking history. We therefore investigated whether reduced lung function is associated with lower blood markers of nutritional status in those men. SUBJECTS AND METHODS: This association was examined in a cross-sectional study of 65 Japanese male current or former smokers aged 50 to 80 years: 48 without COPD (non-COPD group), divided into tertiles according to forced expiratory volume in one second as percent of forced vital capacity (FEV(1)/FVC), and 17 with COPD (COPD group). RESULTS: After adjustment for potential confounders, lower FEV(1)/FVC was significantly associated with lower red blood cell count (RBCc), hemoglobin, and total protein (TP); not with total energy intake. The difference in adjusted RBCc and TP among the non-COPD group tertiles was greater than that between the bottom tertile in the non-COPD group and the COPD group. CONCLUSION: In non-COPD aging men with smoking history, trends toward reduced nutritional status and anemia may independently emerge in blood components along with decreased lung function even before COPD onset.
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spelling pubmed-29216912010-08-16 Lung function and blood markers of nutritional status in non-COPD aging men with smoking history: A cross-sectional study Shiozawa, Nobuyoshi Hayashimoto, Kanae Suzuki, Etsuji Kikuchi, Hiroshi Takata, Shingo Ashida, Kozo Watanabe, Masutaka Hosaki, Yasuhiro Mitsunobu, Fumihiro Int J Chron Obstruct Pulmon Dis Original Research PURPOSE: Cigarette smoking and advanced age are well known as risk factors for chronic obstructive pulmonary disease (COPD), and nutritional abnormalities are important in patients with COPD. However, little is known about the nutritional status in non-COPD aging men with smoking history. We therefore investigated whether reduced lung function is associated with lower blood markers of nutritional status in those men. SUBJECTS AND METHODS: This association was examined in a cross-sectional study of 65 Japanese male current or former smokers aged 50 to 80 years: 48 without COPD (non-COPD group), divided into tertiles according to forced expiratory volume in one second as percent of forced vital capacity (FEV(1)/FVC), and 17 with COPD (COPD group). RESULTS: After adjustment for potential confounders, lower FEV(1)/FVC was significantly associated with lower red blood cell count (RBCc), hemoglobin, and total protein (TP); not with total energy intake. The difference in adjusted RBCc and TP among the non-COPD group tertiles was greater than that between the bottom tertile in the non-COPD group and the COPD group. CONCLUSION: In non-COPD aging men with smoking history, trends toward reduced nutritional status and anemia may independently emerge in blood components along with decreased lung function even before COPD onset. Dove Medical Press 2010 2010-08-09 /pmc/articles/PMC2921691/ /pubmed/20714377 Text en © 2010 Shiozawa et al, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
spellingShingle Original Research
Shiozawa, Nobuyoshi
Hayashimoto, Kanae
Suzuki, Etsuji
Kikuchi, Hiroshi
Takata, Shingo
Ashida, Kozo
Watanabe, Masutaka
Hosaki, Yasuhiro
Mitsunobu, Fumihiro
Lung function and blood markers of nutritional status in non-COPD aging men with smoking history: A cross-sectional study
title Lung function and blood markers of nutritional status in non-COPD aging men with smoking history: A cross-sectional study
title_full Lung function and blood markers of nutritional status in non-COPD aging men with smoking history: A cross-sectional study
title_fullStr Lung function and blood markers of nutritional status in non-COPD aging men with smoking history: A cross-sectional study
title_full_unstemmed Lung function and blood markers of nutritional status in non-COPD aging men with smoking history: A cross-sectional study
title_short Lung function and blood markers of nutritional status in non-COPD aging men with smoking history: A cross-sectional study
title_sort lung function and blood markers of nutritional status in non-copd aging men with smoking history: a cross-sectional study
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921691/
https://www.ncbi.nlm.nih.gov/pubmed/20714377
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