SF2/ASF Autoregulation Involves Multiple Layers of Post-transcriptional and Translational Control

SF2/ASF is a prototypical SR protein, with important roles in splicing and other aspects of mRNA metabolism. SFRS1 (SF2/ASF) is a potent proto-oncogene with abnormal expression in many tumors. We found that SF2/ASF negatively autoregulates its expression to maintain homeostatic levels. We characteri...

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Detalles Bibliográficos
Autores principales: Sun, Shuying, Zhang, Zuo, Sinha, Rahul, Karni, Rotem, Krainer, Adrian R.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921916/
https://www.ncbi.nlm.nih.gov/pubmed/20139984
http://dx.doi.org/10.1038/nsmb.1750

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921916/
https://www.ncbi.nlm.nih.gov/pubmed/20139984
http://dx.doi.org/10.1038/nsmb.1750

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