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SF2/ASF Autoregulation Involves Multiple Layers of Post-transcriptional and Translational Control
SF2/ASF is a prototypical SR protein, with important roles in splicing and other aspects of mRNA metabolism. SFRS1 (SF2/ASF) is a potent proto-oncogene with abnormal expression in many tumors. We found that SF2/ASF negatively autoregulates its expression to maintain homeostatic levels. We characteri...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921916/ https://www.ncbi.nlm.nih.gov/pubmed/20139984 http://dx.doi.org/10.1038/nsmb.1750 |