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Early impact of aortic wrapping on patients undergoing aortic valve replacement with mild to moderate ascending aorta dilatation

BACKGROUND: The management of mild to moderate dilatation of the ascending aorta of less than 5 cm is controversial, particularly when concomitant surgical correction of aortic valve is required. We investigate the impact of a simple method of aorta reduction using Dacron graft wrapping during aorti...

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Autores principales: Ang, Keng-Leong, Raheel, Furqan, Bajaj, Amrita, Sosnowski, Andrzej, Galiñanes, Manuel
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922107/
https://www.ncbi.nlm.nih.gov/pubmed/20691060
http://dx.doi.org/10.1186/1749-8090-5-58
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author Ang, Keng-Leong
Raheel, Furqan
Bajaj, Amrita
Sosnowski, Andrzej
Galiñanes, Manuel
author_facet Ang, Keng-Leong
Raheel, Furqan
Bajaj, Amrita
Sosnowski, Andrzej
Galiñanes, Manuel
author_sort Ang, Keng-Leong
collection PubMed
description BACKGROUND: The management of mild to moderate dilatation of the ascending aorta of less than 5 cm is controversial, particularly when concomitant surgical correction of aortic valve is required. We investigate the impact of a simple method of aorta reduction using Dacron graft wrapping during aortic valve replacement on the rest of the aorta. METHODS: We studied 14 patients who had ascending aorta dilatation of 4-5 cm before undergoing aortic wrapping during their aortic valve replacement and compared with their post-operative imaging within a month. RESULTS: The diameters of the ascending aorta wrapped with the Dacron graft were significantly reduced within 4 weeks after surgery from 44.7 ± 2.6 to 33.6 ± 3.9 mm (p < 0.001). This was associated with significant reduction in the diameter of rest of ascending aorta: coronary sinuses (from 37.9 ± 4.9 mm to 33.3 ± 6.1 mm; p < 0.001), sinotubular junction (from 33.2 ± 4.7 mm to 30.6 ± 4.4 mm, p = 0.02), and aortic arch (from 34.7 ± 4.3 mm to 32.6 ± 4.1 mm, p = 0.03). CONCLUSIONS: Reduction of ascending aortic dilatation by wrapping with a Dacron graft in this preliminary study is associated with favourable early reversed aortic remodelling. This supports the hypothesis that correction of mild-moderate dilatation of the ascending aorta with Dacron wrapping at the time of aortic valve surgery may prevent the progression of the dilatation, although the long-term study on a larger population is needed to confirm its benefits.
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spelling pubmed-29221072010-08-17 Early impact of aortic wrapping on patients undergoing aortic valve replacement with mild to moderate ascending aorta dilatation Ang, Keng-Leong Raheel, Furqan Bajaj, Amrita Sosnowski, Andrzej Galiñanes, Manuel J Cardiothorac Surg Research Article BACKGROUND: The management of mild to moderate dilatation of the ascending aorta of less than 5 cm is controversial, particularly when concomitant surgical correction of aortic valve is required. We investigate the impact of a simple method of aorta reduction using Dacron graft wrapping during aortic valve replacement on the rest of the aorta. METHODS: We studied 14 patients who had ascending aorta dilatation of 4-5 cm before undergoing aortic wrapping during their aortic valve replacement and compared with their post-operative imaging within a month. RESULTS: The diameters of the ascending aorta wrapped with the Dacron graft were significantly reduced within 4 weeks after surgery from 44.7 ± 2.6 to 33.6 ± 3.9 mm (p < 0.001). This was associated with significant reduction in the diameter of rest of ascending aorta: coronary sinuses (from 37.9 ± 4.9 mm to 33.3 ± 6.1 mm; p < 0.001), sinotubular junction (from 33.2 ± 4.7 mm to 30.6 ± 4.4 mm, p = 0.02), and aortic arch (from 34.7 ± 4.3 mm to 32.6 ± 4.1 mm, p = 0.03). CONCLUSIONS: Reduction of ascending aortic dilatation by wrapping with a Dacron graft in this preliminary study is associated with favourable early reversed aortic remodelling. This supports the hypothesis that correction of mild-moderate dilatation of the ascending aorta with Dacron wrapping at the time of aortic valve surgery may prevent the progression of the dilatation, although the long-term study on a larger population is needed to confirm its benefits. BioMed Central 2010-08-06 /pmc/articles/PMC2922107/ /pubmed/20691060 http://dx.doi.org/10.1186/1749-8090-5-58 Text en Copyright ©2010 Ang et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Ang, Keng-Leong
Raheel, Furqan
Bajaj, Amrita
Sosnowski, Andrzej
Galiñanes, Manuel
Early impact of aortic wrapping on patients undergoing aortic valve replacement with mild to moderate ascending aorta dilatation
title Early impact of aortic wrapping on patients undergoing aortic valve replacement with mild to moderate ascending aorta dilatation
title_full Early impact of aortic wrapping on patients undergoing aortic valve replacement with mild to moderate ascending aorta dilatation
title_fullStr Early impact of aortic wrapping on patients undergoing aortic valve replacement with mild to moderate ascending aorta dilatation
title_full_unstemmed Early impact of aortic wrapping on patients undergoing aortic valve replacement with mild to moderate ascending aorta dilatation
title_short Early impact of aortic wrapping on patients undergoing aortic valve replacement with mild to moderate ascending aorta dilatation
title_sort early impact of aortic wrapping on patients undergoing aortic valve replacement with mild to moderate ascending aorta dilatation
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922107/
https://www.ncbi.nlm.nih.gov/pubmed/20691060
http://dx.doi.org/10.1186/1749-8090-5-58
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