Mesenchymal Stem Cells Promote Mammosphere Formation and Decrease E-Cadherin in Normal and Malignant Breast Cells

INTRODUCTION: Normal and malignant breast tissue contains a rare population of multi-potent cells with the capacity to self-renew, referred to as stem cells, or tumor initiating cells (TIC). These cells can be enriched by growth as “mammospheres” in three-dimensional cultures. OBJECTIVE: We tested t...

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Detalles Bibliográficos
Autores principales: Klopp, Ann H., Lacerda, Lara, Gupta, Anshul, Debeb, Bisrat G., Solley, Travis, Li, Li, Spaeth, Erika, Xu, Wei, Zhang, Xiaomei, Lewis, Michael T., Reuben, James M., Krishnamurthy, Savitri, Ferrari, Mauro, Gaspar, Rogério, Buchholz, Thomas A., Cristofanilli, Massimo, Marini, Frank, Andreeff, Michael, Woodward, Wendy A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922340/
https://www.ncbi.nlm.nih.gov/pubmed/20808935
http://dx.doi.org/10.1371/journal.pone.0012180

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