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Hepatic Gene Expression Profiling Reveals Key Pathways Involved in Leptin-Mediated Weight Loss in ob/ob Mice

BACKGROUND: Leptin, a cytokine-like protein, plays an important role in the regulation of body weight through inhibition of food intake and stimulation of energy expenditure. Leptin circulates in blood and acts on the brain, which sends downstream signals to regulate body weight. Leptin therapy has...

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Detalles Bibliográficos
Autores principales:	Sharma, Ashok, Bartell, Shoshana M., Baile, Clifton A., Chen, Bo, Podolsky, Robert H., McIndoe, Richard A., She, Jin-Xiong
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922341/ https://www.ncbi.nlm.nih.gov/pubmed/20808936 http://dx.doi.org/10.1371/journal.pone.0012147

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