Cargando…

The inositol 5-phosphatase SHIP2 regulates endocytic clathrin-coated pit dynamics

Phosphatidylinositol (PI) 4,5-bisphosphate (PI(4,5)P(2)) and its phosphorylated product PI 3,4,5-triphosphate (PI(3,4,5)P(3)) are two major phosphoinositides concentrated at the plasma membrane. Their levels, which are tightly controlled by kinases, phospholipases, and phosphatases, regulate a varie...

Descripción completa

Detalles Bibliográficos
Autores principales: Nakatsu, Fubito, Perera, Rushika M., Lucast, Louise, Zoncu, Roberto, Domin, Jan, Gertler, Frank B., Toomre, Derek, De Camilli, Pietro
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922640/
https://www.ncbi.nlm.nih.gov/pubmed/20679431
http://dx.doi.org/10.1083/jcb.201005018