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Human RASSF7 regulates the microtubule cytoskeleton and is required for spindle formation, Aurora B activation and chromosomal congression during mitosis
RASSF7, a member of the N-terminal Ras association domain family, has increased expression in various cancers and, on the basis of our previous work in Xenopus embryos, may be a regulator of mitosis. In the present study, we address, for the first time, the role of human RASSF7 in mitosis. We demons...
Autores principales: | Recino, Asha, Sherwood, Victoria, Flaxman, Amy, Cooper, Wendy N., Latif, Farida, Ward, Andrew, Chalmers, Andrew D. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922839/ https://www.ncbi.nlm.nih.gov/pubmed/20629633 http://dx.doi.org/10.1042/BJ20100883 |
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