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TRANSWESD: inferring cellular networks with transitive reduction

Motivation: Distinguishing direct from indirect influences is a central issue in reverse engineering of biological networks because it facilitates detection and removal of false positive edges. Transitive reduction is one approach for eliminating edges reflecting indirect effects but its use in reco...

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Detalles Bibliográficos
Autores principales: Klamt, Steffen, Flassig, Robert J., Sundmacher, Kai
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922889/
https://www.ncbi.nlm.nih.gov/pubmed/20605927
http://dx.doi.org/10.1093/bioinformatics/btq342