CD169(+) MACROPHAGES PRESENT LIPID ANTIGENS TO MEDIATE EARLY ACTIVATION OF INVARIANT NKT CELLS IN LYMPH NODES

Invariant NKT (iNKT) cells are involved in host defence against microbial infections. While it is known that iNKT cells recognize glycolipids presented by CD1d, how and where they encounter antigen in vivo remains unclear. We used multi-photon microscopy to visualize the dynamics and activation of i...

Descripción completa

Detalles Bibliográficos
Autores principales: Barral, Patricia, Polzella, Paolo, Bruckbauer, Andreas, van Rooijen, Nico, Besra, Gurdyal S., Cerundolo, Vincenzo, Batista, Facundo D.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923071/
https://www.ncbi.nlm.nih.gov/pubmed/20228797
http://dx.doi.org/10.1038/ni.1853

Ejemplares similares

Ejemplares similares