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Overexpression of hTERT increases stem-like properties and decreases spontaneous differentiation in human mesenchymal stem cell lines
To overcome loss of stem-like properties and spontaneous differentiation those hinder the expansion and application of human mesenchymal stem cells (hMSCs), we have clonally isolated permanent and stable human MSC lines by ectopic overexpression of primary cell cultures of hMSCs with HPV 16 E6E7 and...
Autores principales: | Tsai, Chih-Chien, Chen, Chun-Li, Liu, Hwa-Chung, Lee, Yi-Ting, Wang, Hsei-Wei, Hou, Lein-Tuan, Hung, Shih-Chieh |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923118/ https://www.ncbi.nlm.nih.gov/pubmed/20670406 http://dx.doi.org/10.1186/1423-0127-17-64 |
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