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Delta-Like 4 Differentially Regulates Murine CD4(+) T Cell Expansion via BMI1
BACKGROUND: Studies have shown that Notch is essential for the maintenance of a T cell Th2 phenotype in vivo. It has also been shown that Notch ligands have diverse functions during T cell activation. We chose to investigate the role of Notch ligands during the Th2 response. PRINCIPAL FINDINGS: We s...
Autores principales: | Schaller, Matthew A., Logue, Hannah, Mukherjee, Sumanta, Lindell, Dennis M., Coelho, Ana Lucia, Lincoln, Pamela, Carson, William F., Ito, Toshihiro, Cavassani, Karen A., Chensue, Stephen W., Hogaboam, Cory M., Lukacs, Nicholas W., Kunkel, Steven L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923143/ https://www.ncbi.nlm.nih.gov/pubmed/20808960 http://dx.doi.org/10.1371/journal.pone.0012172 |
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