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Expansion of Cord Blood CD34(+) Cells in Presence of zVADfmk and zLLYfmk Improved Their In Vitro Functionality and In Vivo Engraftment in NOD/SCID Mouse

BACKGROUND: Cord blood (CB) is a promising source for hematopoietic stem cell transplantations. The limitation of cell dose associated with this source has prompted the ex vivo expansion of hematopoietic stem and progenitor cells (HSPCs). However, the expansion procedure is known to exhaust the stem...

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Detalles Bibliográficos
Autores principales:	M, Sangeetha V., Kale, Vaijayanti P., Limaye, Lalita S.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923186/ https://www.ncbi.nlm.nih.gov/pubmed/20808921 http://dx.doi.org/10.1371/journal.pone.0012221

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