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Genomic Views of Distant-Acting Enhancers

In contrast to changes in protein-coding sequences, the significance of noncoding DNA variation in human disease has been minimally explored. A recent torrent of genome-wide association studies suggests that noncoding variation represents a significant risk factor for common disorders, but the mecha...

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Detalles Bibliográficos
Autores principales:	Visel, Axel, Rubin, Edward M., Pennacchio, Len A.
Formato:	Texto
Lenguaje:	English
Publicado:	2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923221/ https://www.ncbi.nlm.nih.gov/pubmed/19741700 http://dx.doi.org/10.1038/nature08451

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