Aquaporins in Sensory and Pain Transmission

Recent data suggest a possible involvement of Aquaporins (AQPs) in pain transmission. AQPs are small membrane channel proteins involved in osmoregulation and, to date, AQP1, AQP2, AQP3, AQP4, AQP5, AQP8 and AQP9 have been found in the nervous system. Nevertheless only AQP1, AQP2 and AQP4 seem to be...

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Detalles Bibliográficos
Autor principal: Borsani, Elisa
Formato: Texto
Lenguaje:English
Publicado: Bentham Science Publishers Ltd 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923366/
https://www.ncbi.nlm.nih.gov/pubmed/21119883
http://dx.doi.org/10.2174/157015910791233187
Descripción
Sumario:Recent data suggest a possible involvement of Aquaporins (AQPs) in pain transmission. AQPs are small membrane channel proteins involved in osmoregulation and, to date, AQP1, AQP2, AQP3, AQP4, AQP5, AQP8 and AQP9 have been found in the nervous system. Nevertheless only AQP1, AQP2 and AQP4 seem to be involved in nociception. In this review, direct and indirect evidences of the role of AQPs in pain processing will be reported.

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