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Aquaporins in Sensory and Pain Transmission

Recent data suggest a possible involvement of Aquaporins (AQPs) in pain transmission. AQPs are small membrane channel proteins involved in osmoregulation and, to date, AQP1, AQP2, AQP3, AQP4, AQP5, AQP8 and AQP9 have been found in the nervous system. Nevertheless only AQP1, AQP2 and AQP4 seem to be...

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Detalles Bibliográficos
Autor principal: Borsani, Elisa
Formato: Texto
Lenguaje:English
Publicado: Bentham Science Publishers Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923366/
https://www.ncbi.nlm.nih.gov/pubmed/21119883
http://dx.doi.org/10.2174/157015910791233187
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author Borsani, Elisa
author_facet Borsani, Elisa
author_sort Borsani, Elisa
collection PubMed
description Recent data suggest a possible involvement of Aquaporins (AQPs) in pain transmission. AQPs are small membrane channel proteins involved in osmoregulation and, to date, AQP1, AQP2, AQP3, AQP4, AQP5, AQP8 and AQP9 have been found in the nervous system. Nevertheless only AQP1, AQP2 and AQP4 seem to be involved in nociception. In this review, direct and indirect evidences of the role of AQPs in pain processing will be reported.
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spelling pubmed-29233662010-12-01 Aquaporins in Sensory and Pain Transmission Borsani, Elisa Curr Neuropharmacol Article Recent data suggest a possible involvement of Aquaporins (AQPs) in pain transmission. AQPs are small membrane channel proteins involved in osmoregulation and, to date, AQP1, AQP2, AQP3, AQP4, AQP5, AQP8 and AQP9 have been found in the nervous system. Nevertheless only AQP1, AQP2 and AQP4 seem to be involved in nociception. In this review, direct and indirect evidences of the role of AQPs in pain processing will be reported. Bentham Science Publishers Ltd 2010-06 /pmc/articles/PMC2923366/ /pubmed/21119883 http://dx.doi.org/10.2174/157015910791233187 Text en ©2010 Bentham Science Publishers Ltd. http://creativecommons.org/licenses/by/2.5/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.5/), which permits unrestrictive use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Article
Borsani, Elisa
Aquaporins in Sensory and Pain Transmission
title Aquaporins in Sensory and Pain Transmission
title_full Aquaporins in Sensory and Pain Transmission
title_fullStr Aquaporins in Sensory and Pain Transmission
title_full_unstemmed Aquaporins in Sensory and Pain Transmission
title_short Aquaporins in Sensory and Pain Transmission
title_sort aquaporins in sensory and pain transmission
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923366/
https://www.ncbi.nlm.nih.gov/pubmed/21119883
http://dx.doi.org/10.2174/157015910791233187
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