Unique DNA Repair Gene Variations and Potential Associations with the Primary Antibody Deficiency Syndromes IgAD and CVID

BACKGROUND: Despite considerable effort, the genetic factors responsible for >90% of the antibody deficiency syndromes IgAD and CVID remain elusive. To produce a functionally diverse antibody repertoire B lymphocytes undergo class switch recombination. This process is initiated by AID-catalyzed d...

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Detalles Bibliográficos
Autores principales: Offer, Steven M., Pan-Hammarström, Qiang, Hammarström, Lennart, Harris, Reuben S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923613/
https://www.ncbi.nlm.nih.gov/pubmed/20805886
http://dx.doi.org/10.1371/journal.pone.0012260

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