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UV Damage in DNA Promotes Nucleosome Unwrapping

The association of DNA with histones in chromatin impedes DNA repair enzymes from accessing DNA lesions. Nucleosomes exist in a dynamic equilibrium in which portions of the DNA molecule spontaneously unwrap, transiently exposing buried DNA sites. Thus, nucleosome dynamics in certain regions of chrom...

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Detalles Bibliográficos
Autores principales:	Duan, Ming-Rui, Smerdon, Michael J.
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2010
Materias:	DNA and Chromosomes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924050/ https://www.ncbi.nlm.nih.gov/pubmed/20562439 http://dx.doi.org/10.1074/jbc.M110.140087

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