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MetMap Enables Genome-Scale Methyltyping for Determining Methylation States in Populations
The ability to assay genome-scale methylation patterns using high-throughput sequencing makes it possible to carry out association studies to determine the relationship between epigenetic variation and phenotype. While bisulfite sequencing can determine a methylome at high resolution, cost inhibits...
Autores principales: | Singer, Meromit, Boffelli, Dario, Dhahbi, Joseph, Schönhuth, Alexander, Schroth, Gary P., Martin, David I. K., Pachter, Lior |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924245/ https://www.ncbi.nlm.nih.gov/pubmed/20856582 http://dx.doi.org/10.1371/journal.pcbi.1000888 |
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