Cargando…

Parthenolide induces proliferation inhibition and apoptosis of pancreatic cancer cells in vitro

BACKGROUND: To explore the anti-tumor effects of parthenolide in human pancreatic cancer. METHODS: BxPC-3 cell, a human pancreatic cancer, was treated with parthenolide at different concentrations. The MTT assay was used to analyze cell viability. Flow cytometry and DNA fragmentation analysis were a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Jun-Wei, Cai, Min-Xia, Xin, Ying, Wu, Qing-Song, Ma, Jun, Yang, Po, Xie, Hai-Yang, Huang, Dong-Sheng
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924280/ https://www.ncbi.nlm.nih.gov/pubmed/20698986 http://dx.doi.org/10.1186/1756-9966-29-108

Ejemplares similares

Parthenolide suppresses pancreatic cell growth by autophagy-mediated apoptosis
por: Liu, Weifeng, et al.
Publicado: (2017)

Parthenolide Induces Apoptosis and Cell Cycle Arrest of Human 5637 Bladder Cancer Cells In Vitro
por: Cheng, Guang, et al.
Publicado: (2011)

Parthenolide and arsenic trioxide co-trigger autophagy-accompanied apoptosis in hepatocellular carcinoma cells
por: Yi, Juan, et al.
Publicado: (2022)

Parthenolide Induces ROS-Mediated Apoptosis in Lymphoid Malignancies
por: Jorge, Joana, et al.
Publicado: (2023)

Parthenolide reveals an allosteric mode to inhibit the deISGylation activity of SARS-CoV‑2 papain-like protease: Parthenolide covalently inhibits papain-like protease
por: Zou, Zhihui, et al.
Publicado: (2022)

Parthenolide leads to proteomic differences in thyroid cancer cells and promotes apoptosis
por: Cui, Meng, et al.
Publicado: (2022)

Costunolide and Parthenolide Ameliorate MPP+ Induced Apoptosis in the Cellular Parkinson’s Disease Model
por: Arslan, Mehmet Enes, et al.
Publicado: (2023)

Parthenolide Inhibits Angiogenesis in Esophageal Squamous Cell Carcinoma Through Suppression of VEGF
por: Tian, Bo, et al.
Publicado: (2020)

Parthenolide Inhibits the Proliferation of MDA-T32 Papillary Thyroid Carcinoma Cells in Vitro and in Mouse Tumor Xenografts and Activates Autophagy and Apoptosis by Downregulation of the Mammalian Target of Rapamycin (mTOR)/PI3K/AKT Signaling Pathway
por: Li, Chao, et al.
Publicado: (2019)

Parthenolide Inhibits STAT3 Signaling by Covalently Targeting Janus Kinases
por: Liu, Man, et al.
Publicado: (2018)

Inhibition of microtubule detyrosination by parthenolide facilitates functional CNS axon regeneration
por: Leibinger, Marco, et al.
Publicado: (2023)

Parthenolide induces apoptosis and lytic cytotoxicity in Epstein-Barr virus-positive Burkitt lymphoma
por: LI, YUAN, et al.
Publicado: (2012)

Parthenolide facilitates apoptosis and reverses drug-resistance of human gastric carcinoma cells by inhibiting the STAT3 signaling pathway
por: Li, Hua, et al.
Publicado: (2018)

Nano Parthenolide Improves Intestinal Barrier Function of Sepsis by Inhibiting Apoptosis and ROS via 5-HTR2A
por: Guo, Ning-Ke, et al.
Publicado: (2023)

Anti-Inflammatory and Antiosteoclastogenic Activities of Parthenolide on Human Periodontal Ligament Cells In Vitro
por: Zhang, Xufang, et al.
Publicado: (2014)

Retracted: Parthenolide Inhibits the Proliferation of MDA-T32 Papillary Thyroid Carcinoma Cells In Vitro and in Mouse Tumor Xenografts and Activates Autophagy and Apoptosis by Downregulation of the Mammalian Target of Rapamycin (mTOR)/PI3K/AKT Signaling Pathway
por: Li, Chao, et al.
Publicado: (2021)

Ursolic Acid Inhibits Proliferation and Induces Apoptosis of Cancer Cells In Vitro and In Vivo
por: Wang, Xuemei, et al.
Publicado: (2011)

Parthenolide Inhibits Cancer Stem-Like Side Population of Nasopharyngeal Carcinoma Cells via Suppression of the NF-κB/COX-2 Pathway
por: Liao, Kun, et al.
Publicado: (2015)

The Emerging Potential of Parthenolide Nanoformulations in Tumor Therapy
por: An, Tao, et al.
Publicado: (2022)

Parthenolide-induced apoptosis of hepatic stellate cells and anti-fibrotic effects in an in vivo rat model
por: Kim, In Hee, et al.
Publicado: (2012)

Synergy between parthenolide and arsenic trioxide in adult T-cell leukemia/lymphoma cells in vitro
por: Kouhpaikar, Hamideh, et al.
Publicado: (2020)

Parthenolide promotes apoptotic cell death and inhibits the migration and invasion of SW620 cells
por: Liu, Yu Chuan, et al.
Publicado: (2017)

Parthenolide generates reactive oxygen species and autophagy in MDA-MB231 cells. A soluble parthenolide analogue inhibits tumour growth and metastasis in a xenograft model of breast cancer
por: D'Anneo, A, et al.
Publicado: (2013)

Parthenolide Has Negative Effects on In Vitro Enhanced Osteogenic Phenotypes by Inflammatory Cytokine TNF-α via Inhibiting JNK Signaling
por: Park, Jin-Ho, et al.
Publicado: (2020)

(E)-13-(4-Aminophenyl)parthenolide
por: Penthala, Narsimha Reddy, et al.
Publicado: (2013)

Derivatisation of parthenolide to address chemoresistant chronic lymphocytic leukaemia
por: Li, Xingjian, et al.
Publicado: (2019)

Moringa oleifera Lam. Isothiocyanate Quinazolinone Derivatives Inhibit U251 Glioma Cell Proliferation through Cell Cycle Regulation and Apoptosis Induction
por: Xie, Jing, et al.
Publicado: (2023)

CRKL overexpression promotes cell proliferation and inhibits apoptosis in endometrial carcinoma
por: Cai, Le, et al.
Publicado: (2017)

First Discovery of Cholesterol-Lowering Activity of Parthenolide as NPC1L1 Inhibitor
por: Liu, Wenjing, et al.
Publicado: (2022)

Parthenolide induces apoptosis via TNFRSF10B and PMAIP1 pathways in human lung cancer cells
por: Zhao, Xiaofei, et al.
Publicado: (2014)

Hsp72 Is an Intracellular Target of the α,β-Unsaturated Sesquiterpene Lactone, Parthenolide
por: Shin, Myungsun, et al.
Publicado: (2017)

Involvement of Akt/NF-κB pathway in antitumor effects of parthenolide on glioblastoma cells in vitro and in vivo
por: Nakabayashi, Hiromichi, et al.
Publicado: (2012)

Untargeted lipidomic analysis and network pharmacology for parthenolide treated papillary thyroid carcinoma cells
por: Huang, Le-Tian, et al.
Publicado: (2023)

Cell death in amastigote forms of Leishmania amazonensis induced by parthenolide
por: Tiuman, Tatiana Shioji, et al.
Publicado: (2014)

Crystal structure of (E)-13-(pyrimidin-5-yl)parthenolide
por: Bommagani, Shobanbabu, et al.
Publicado: (2015)

Parthenolide: a novel pharmacological approach to promote nerve regeneration
por: Diekmann, Heike, et al.
Publicado: (2016)

Parthenolide as Cooperating Agent for Anti-Cancer Treatment of Various Malignancies
por: Sztiller-Sikorska, Malgorzata, et al.
Publicado: (2020)

Parthenolide Suppresses T Helper 17 and Alleviates Experimental Autoimmune Encephalomyelitis
por: Zhang, Zhihui, et al.
Publicado: (2022)

Parthenolide and Its Soluble Analogues: Multitasking Compounds with Antitumor Properties
por: Carlisi, Daniela, et al.
Publicado: (2022)

Parthenolide Attenuates Sepsis-Induced Acute Kidney Injury in Rats by Reducing Inflammation
por: Shou, Di-Wen, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_qsnlc2gnjci2pd77nn4b0nrfp4