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Up-regulation of p21 and TNF-α is mediated in lycorine-induced death of HL-60 cells
BACKGROUND: Leukemia is one of the most life-threatening cancers today, and acute promyelogenous leukemia (APL) is a common type of leukemia. Many natural compounds have already been found to exhibit significant anti-tumor effects. Lycorine, a natural alkaloid extracted from Amaryllidaceae, exhibite...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924328/ https://www.ncbi.nlm.nih.gov/pubmed/20682078 http://dx.doi.org/10.1186/1475-2867-10-25 |