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Variations in TcdB Activity and the Hypervirulence of Emerging Strains of Clostridium difficile

Hypervirulent strains of Clostridium difficile have emerged over the past decade, increasing the morbidity and mortality of patients infected by this opportunistic pathogen. Recent work suggested the major C. difficile virulence factor, TcdB, from hypervirulent strains (TcdB(HV)) was more cytotoxic...

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Detalles Bibliográficos
Autores principales: Lanis, Jordi M., Barua, Soumitra, Ballard, Jimmy D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924371/
https://www.ncbi.nlm.nih.gov/pubmed/20808849
http://dx.doi.org/10.1371/journal.ppat.1001061