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Variations in TcdB Activity and the Hypervirulence of Emerging Strains of Clostridium difficile
Hypervirulent strains of Clostridium difficile have emerged over the past decade, increasing the morbidity and mortality of patients infected by this opportunistic pathogen. Recent work suggested the major C. difficile virulence factor, TcdB, from hypervirulent strains (TcdB(HV)) was more cytotoxic...
Autores principales: | Lanis, Jordi M., Barua, Soumitra, Ballard, Jimmy D. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924371/ https://www.ncbi.nlm.nih.gov/pubmed/20808849 http://dx.doi.org/10.1371/journal.ppat.1001061 |
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