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The Pancreatic and Duodenal Homeobox Protein PDX-1 Regulates the Ductal Specific Keratin 19 through the Degradation of MEIS1 and DNA Binding

BACKGROUND: Pancreas organogenesis is the result of well-orchestrated and balanced activities of transcription factors. The homeobox transcription factor PDX-1 plays a crucial role in the development and function of the pancreas, both in the maintenance of progenitor cells and in determination and m...

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Detalles Bibliográficos
Autores principales: von Burstin, Johannes, Reichert, Maximilian, Wescott, Melanie P., Rustgi, Anil K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924401/
https://www.ncbi.nlm.nih.gov/pubmed/20808819
http://dx.doi.org/10.1371/journal.pone.0012311