Replication dependent instability at (CTG)•(CAG) repeat hairpins in human cells

Instability of (CTG)•(CAG) microsatellite trinucleotide repeat (TNR) sequences is responsible for more than one dozen neurological or neuromuscular diseases. TNR instability during DNA synthesis is thought to involve slipped strand or hairpin structures in template or nascent DNA strands, although d...

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Detalles Bibliográficos
Autores principales: Liu, Guoqi, Chen, Xiaomi, Bissler, John J., Sinden, Richard R., Leffak, Michael
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924473/
https://www.ncbi.nlm.nih.gov/pubmed/20676085
http://dx.doi.org/10.1038/nchembio.416

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924473/
https://www.ncbi.nlm.nih.gov/pubmed/20676085
http://dx.doi.org/10.1038/nchembio.416

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