Corecognition of DNA and a methylated histone tail by MSL3 chromodomain

MSL3 resides in the MSL (male-specific-lethal) complex that upregulates transcription by spreading the H4K16 acetyl-mark. We discovered a DNA-dependent interaction of MSL3 chromodomain with the histone H4K20 monomethyl-mark. Structure of a ternary complex shows DNA minor groove accommodates the hist...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Daesung, Blus, Bartlomiej J., Chandra, Vikas, Huang, Pengxiang, Rastinejad, Fraydoon, Khorasanizadeh, Sepideh
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924628/
https://www.ncbi.nlm.nih.gov/pubmed/20657587
http://dx.doi.org/10.1038/nsmb.1856

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924628/
https://www.ncbi.nlm.nih.gov/pubmed/20657587
http://dx.doi.org/10.1038/nsmb.1856

Ejemplares similares