Single-molecule dynamics of nuclear mRNA

In eukaryotes, mRNA molecules are transcribed from nuclear DNA and commute through a labyrinth of nucleoplasmic passageways to the nuclear envelope where they are exported to the cytoplasm. New findings provide tools and insights into the biophysical properties that govern mRNA translocations en rou...

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Detalles Bibliográficos
Autores principales: Shav-Tal, Yaron, Gruenbaum, Yosef
Formato: Texto
Lenguaje:English
Publicado: Biology Reports Ltd 2009
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924697/
https://www.ncbi.nlm.nih.gov/pubmed/20948657
http://dx.doi.org/10.3410/B1-29
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author Shav-Tal, Yaron
Gruenbaum, Yosef
author_facet Shav-Tal, Yaron
Gruenbaum, Yosef
author_sort Shav-Tal, Yaron
collection PubMed
description In eukaryotes, mRNA molecules are transcribed from nuclear DNA and commute through a labyrinth of nucleoplasmic passageways to the nuclear envelope where they are exported to the cytoplasm. New findings provide tools and insights into the biophysical properties that govern mRNA translocations en route to the cytoplasm and suggest that mRNA molecules move in a discontinuous manner due to transient interactions with the nuclear environment.
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spelling pubmed-29246972010-10-14 Single-molecule dynamics of nuclear mRNA Shav-Tal, Yaron Gruenbaum, Yosef F1000 Biol Rep Review Article In eukaryotes, mRNA molecules are transcribed from nuclear DNA and commute through a labyrinth of nucleoplasmic passageways to the nuclear envelope where they are exported to the cytoplasm. New findings provide tools and insights into the biophysical properties that govern mRNA translocations en route to the cytoplasm and suggest that mRNA molecules move in a discontinuous manner due to transient interactions with the nuclear environment. Biology Reports Ltd 2009-04-29 /pmc/articles/PMC2924697/ /pubmed/20948657 http://dx.doi.org/10.3410/B1-29 Text en © 2009 Biology Reports Ltd http://creativecommons.org/licenses/by-nc/3.0/legalcode This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. You may not use this work for commercial purposes
spellingShingle Review Article
Shav-Tal, Yaron
Gruenbaum, Yosef
Single-molecule dynamics of nuclear mRNA
title Single-molecule dynamics of nuclear mRNA
title_full Single-molecule dynamics of nuclear mRNA
title_fullStr Single-molecule dynamics of nuclear mRNA
title_full_unstemmed Single-molecule dynamics of nuclear mRNA
title_short Single-molecule dynamics of nuclear mRNA
title_sort single-molecule dynamics of nuclear mrna
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924697/
https://www.ncbi.nlm.nih.gov/pubmed/20948657
http://dx.doi.org/10.3410/B1-29
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AT gruenbaumyosef singlemoleculedynamicsofnuclearmrna

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