Lessons from the failure of the adenovector HIV vaccine

The much-publicised halting of the joint Merck/HIV Vaccine Trials Network phase IIB candidate HIV-1 vaccine trial in 2007 has led to an unprecedented degree of discussion and introspection amongst the HIV research community. In this commentary, we will summarise the lessons learned from the trial an...

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Detalles Bibliográficos
Autores principales: Blais, Marie-Eve, Rowland-Jones, Sarah
Formato: Texto
Lenguaje:English
Publicado: Biology Reports Ltd 2009
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924706/
https://www.ncbi.nlm.nih.gov/pubmed/20948634
http://dx.doi.org/10.3410/B1-50
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author Blais, Marie-Eve
Rowland-Jones, Sarah
author_facet Blais, Marie-Eve
Rowland-Jones, Sarah
author_sort Blais, Marie-Eve
collection PubMed
description The much-publicised halting of the joint Merck/HIV Vaccine Trials Network phase IIB candidate HIV-1 vaccine trial in 2007 has led to an unprecedented degree of discussion and introspection amongst the HIV research community. In this commentary, we will summarise the lessons learned from the trial and examine the current state of HIV vaccine research.
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spelling pubmed-29247062010-10-14 Lessons from the failure of the adenovector HIV vaccine Blais, Marie-Eve Rowland-Jones, Sarah F1000 Biol Rep Review Article The much-publicised halting of the joint Merck/HIV Vaccine Trials Network phase IIB candidate HIV-1 vaccine trial in 2007 has led to an unprecedented degree of discussion and introspection amongst the HIV research community. In this commentary, we will summarise the lessons learned from the trial and examine the current state of HIV vaccine research. Biology Reports Ltd 2009-06-29 /pmc/articles/PMC2924706/ /pubmed/20948634 http://dx.doi.org/10.3410/B1-50 Text en © 2009 Biology Reports Ltd http://creativecommons.org/licenses/by-nc/3.0/legalcode This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. You may not use this work for commercial purposes
spellingShingle Review Article
Blais, Marie-Eve
Rowland-Jones, Sarah
Lessons from the failure of the adenovector HIV vaccine
title Lessons from the failure of the adenovector HIV vaccine
title_full Lessons from the failure of the adenovector HIV vaccine
title_fullStr Lessons from the failure of the adenovector HIV vaccine
title_full_unstemmed Lessons from the failure of the adenovector HIV vaccine
title_short Lessons from the failure of the adenovector HIV vaccine
title_sort lessons from the failure of the adenovector hiv vaccine
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924706/
https://www.ncbi.nlm.nih.gov/pubmed/20948634
http://dx.doi.org/10.3410/B1-50
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