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Radiographic severity of knee osteoarthritis is conditional on interleukin 1 receptor antagonist gene variations

BACKGROUND: A lack of biomarkers that identify patients at risk for severe osteoarthritis (OA) complicates development of disease-modifying OA drugs. OBJECTIVE: To determine whether inflammatory genetic markers could stratify patients with knee OA into high and low risk for destructive disease. METH...

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Detalles Bibliográficos
Autores principales: Attur, Mukundan, Wang, Hwa-Ying, Kraus, Virginia Byers, Bukowski, Jack F, Aziz, Nazneen, Krasnokutsky, Svetlana, Samuels, Jonathan, Greenberg, Jeffrey, McDaniel, Gary, Abramson, Steven B, Kornman, Kenneth S
Formato: Texto
Lenguaje:English
Publicado: BMJ Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925146/
https://www.ncbi.nlm.nih.gov/pubmed/19934104
http://dx.doi.org/10.1136/ard.2009.113043