Staging of Alzheimer's Pathology in Triple Transgenic Mice: A Light and Electron Microscopic Analysis

The age-related pathological cascade underlying intraneuronal tau formation in 3xTg-AD mice, which harbor the human APP(Swe), PS1(M126V) , and Tau(P301L) gene mutations, remains unclear. At 3 weeks of age, AT180, Alz50, MC1, AT8, and PHF-1 intraneuronal immunoreactivity appeared in the amygdala and...

Descripción completa

Detalles Bibliográficos
Autores principales: Oh, Kwang-Jin, Perez, Sylvia E., Lagalwar, Sarita, Vana, Laurel, Binder, Lester, Mufson, Elliott J.
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925282/
https://www.ncbi.nlm.nih.gov/pubmed/20798886
http://dx.doi.org/10.4061/2010/780102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925282/
https://www.ncbi.nlm.nih.gov/pubmed/20798886
http://dx.doi.org/10.4061/2010/780102

Ejemplares similares