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Staging of Alzheimer's Pathology in Triple Transgenic Mice: A Light and Electron Microscopic Analysis

The age-related pathological cascade underlying intraneuronal tau formation in 3xTg-AD mice, which harbor the human APP(Swe), PS1(M126V) , and Tau(P301L) gene mutations, remains unclear. At 3 weeks of age, AT180, Alz50, MC1, AT8, and PHF-1 intraneuronal immunoreactivity appeared in the amygdala and...

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Detalles Bibliográficos
Autores principales:	Oh, Kwang-Jin, Perez, Sylvia E., Lagalwar, Sarita, Vana, Laurel, Binder, Lester, Mufson, Elliott J.
Formato:	Texto
Lenguaje:	English
Publicado:	SAGE-Hindawi Access to Research 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925282/ https://www.ncbi.nlm.nih.gov/pubmed/20798886 http://dx.doi.org/10.4061/2010/780102

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