Acyclovir inhibition of IDO to decrease Tregs as a glioblastoma treatment adjunct

Regulatory T cells, Tregs, are a subset of lymphocytes that have immunosuppressive attributes. They are elevated in blood of glioblastoma patients and within this tumor's tissue itself. Indoleamine 2,3-dioxygenase, IDO, converts tryptophan to kynurenine. IDO activity enhances Treg formation by...

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Detalles Bibliográficos
Autores principales: Söderlund, Johan, Erhardt, Sophie, Kast, Richard E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925358/
https://www.ncbi.nlm.nih.gov/pubmed/20691089
http://dx.doi.org/10.1186/1742-2094-7-44

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925358/
https://www.ncbi.nlm.nih.gov/pubmed/20691089
http://dx.doi.org/10.1186/1742-2094-7-44

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