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Evolutionary fates within a microbial population highlight an essential role for protein folding during natural selection

Systems biology can offer a great deal of insight into evolution by quantitatively linking complex properties such as protein structure, folding, and function to the fitness of an organism. Although the link between diseases such as Alzheimer's and misfolding is well appreciated, directly showi...

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Detalles Bibliográficos
Autores principales: Peña, Matthew I, Davlieva, Milya, Bennett, Matthew R, Olson, John S, Shamoo, Yousif
Formato: Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925523/
https://www.ncbi.nlm.nih.gov/pubmed/20631681
http://dx.doi.org/10.1038/msb.2010.43