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Distinct Changes in cAMP and Extracellular Signal-Regulated Protein Kinase Signalling in L-DOPA-Induced Dyskinesia
BACKGROUND: In rodents, the development of dyskinesia produced by L-DOPA in the dopamine-depleted striatum occurs in response to increased dopamine D1 receptor-mediated activation of the cAMP - protein kinase A and of the Ras-extracellular signal-regulated kinase (ERK) signalling pathways. However,...
Autores principales: | Santini, Emanuela, Sgambato-Faure, Veronique, Li, Qin, Savasta, Marc, Dovero, Sandra, Fisone, Gilberto, Bezard, Erwan |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925943/ https://www.ncbi.nlm.nih.gov/pubmed/20808799 http://dx.doi.org/10.1371/journal.pone.0012322 |
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