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Presaging Critical Residues in Protein interfaces-Web Server (PCRPi-W): A Web Server to Chart Hot Spots in Protein Interfaces

BACKGROUND: It is well established that only a portion of residues that mediate protein-protein interactions (PPIs), the so-called hot spot, contributes the most to the total binding energy, and thus its identification is an important and relevant question that has clear applications in drug discove...

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Detalles Bibliográficos
Autores principales: Segura Mora, Joan, Assi, Salam A., Fernandez-Fuentes, Narcis
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925954/
https://www.ncbi.nlm.nih.gov/pubmed/20808810
http://dx.doi.org/10.1371/journal.pone.0012352